卢敏课题组(卢敏实验室)
上海交通大学医学院附属瑞金医院上海血液学研究所医学基因组学国家重点实验室
1、Lu, Min; Wu, Jiale; Song, Huaxin. PANDA as a novel therapeutic, PCT/CN2018/085190。进入中国、美国、欧盟、日本、澳大利亚、加拿大等全球主要国家,完成高水平转化。
2、Lu, Min; Wu, Jiale; Song, Huaxin. mp53 rescue compounds and methods of treating a p53 disorder, PCT/CN2019/070117。进入中国、美国、欧盟、日本、澳大利亚、加拿大等全球主要国家,完成高水平转化。
3、临床试验Arsenic Trioxide in Refractory Solid Tumors with Rescuable p53 Mutation (https://www.clinicaltrials.gov/ct2/show/NCT04869475)
4、临床试验Mutant p53-based Personalized Trial Using Decitabine and Arsenic Trioxide on AML/MDS (https://www.clinicaltrials.gov/ct2/show/NCT03855371)
5、临床试验Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations (https://www.clinicaltrials.gov/ct2/show/NCT04906031)
6、临床建议http://tp53.co.uk/interview-with-min-lu/
7、临床建议https://www.anticancerfund.org/en/blog/latest-news-about-drug-repurposing-oncology-4