卢敏课题组(卢敏实验室)
上海交通大学医学院附属瑞金医院上海血液学研究所医学基因组学国家重点实验室
1、Chen S, Wu J, Liang Y, Tang Y, Song H… Lu X, Chen SJ, Lu M, Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site, Cancer Cell, 2021, 39(2): 225-239
https://pubmed.ncbi.nlm.nih.gov/33357454/
2、Tang Y, Song H, Wang Z, Xiao S… Liu F, Wu Y, Lu M, Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations, Cell Rep, 2022, 39(2):110622
https://pubmed.ncbi.nlm.nih.gov/35417717/
3、Wang Z, Zhao Y, Wang Q, Xing Y, Feng L, Kong J… Zhang L, Yang H, Lu M, Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 Mpro, Signal Transduct Target Ther, 2021, 6(1):214
https://pubmed.ncbi.nlm.nih.gov/34075025/
4、Yan N, Li Y, Xing Y, Wu J, Li J… Lu M, Developmental arsenic exposure impairs cognition, directly targets DNMT3A, and reduces DNA methylation, EMBO Rep, 2022, e54147
https://pubmed.ncbi.nlm.nih.gov/35373418/
5、Wu J, Li Y, Wu J, Song H, Tang Y… Zhang S, Lu M, Decitabine activates type I interferon signaling to inhibit p53-deficient myeloid malignant cells, Clin Transl Med, 2021, (11):e593